Home / How it works
Three stages from a tumor biopsy and a matched blood sample to a vaccine ready for administration in your clinic, plus a follow-up loop that turns every patient's outcome into a better design for the next.
Once a case is accepted, we send a single prepaid box to your clinic containing everything you need. No software to install, no portal to log into, no special handling beyond what your team already does for biopsy specimens.
What's in the kit
You collect during the procedure you were already doing
The two samples we need come from steps your team is already performing, with no new clinical workflow:
That's the entirety of your team's collection workflow. We handle everything from courier pickup onwards.
This is where the science happens, and it's also where the tool does the most work on your behalf. The samples go to our sequencing partner. From there, our pipeline reads the dog's tumor DNA, compares it to the dog's healthy DNA, and identifies the mutations that make the tumor different from the rest of the body. Each mutation is then scored for how likely it is to trigger that specific dog's immune system, using prediction models trained on canine biology rather than human.
You don't have to be a bioinformatician to use it. The tool does the heavy analysis, flags the calls worth attention, and presents each option in plain language: what each target is, how confident we are in it, what including or excluding it means for the final vaccine. The recommendations are already made; your job is to review them and make the final call.
Most cases take a clinician under twenty minutes to review. You see what we see, you have everything you need to decide, and the design report we send out at the end is yours to keep, whether you proceed with the vaccine or not.
Our team is available if you want to talk a specific call through, but the tool is designed so you don't have to.
From target list to manufactured vaccine
Picking the right mutations to target is only part of the job. Turning that list into mRNA that will actually work in a dog's body is the other half, and it's where most of the engineering effort behind RosieVaccine lives.
Once the target list is locked, our tool builds and optimizes the vaccine across every variable that affects how well it will work in your patient:
A well-designed vaccine manufactured badly is worse than no vaccine at all, so we work with a single, vetted CDMO partner for every case. The same manufacturing process, the same quality controls, the same handoff, every time.
The finished vaccine ships directly back to your clinic in a labeled box, with nothing left to figure out at the front desk.
What's in the return box
Follow-up moves to the owner's phone
After administration, follow-up moves to the owner's phone. The outcomes app prompts the owner for short, structured wellness check-ins (appetite, energy, mobility, side effects, photos of any visible tumor sites) on a schedule aligned to the dosing calendar.
The owner does the daily work; your clinic sees the aggregated trends in a clinician dashboard before each follow-up visit, with anything concerning flagged for your review.
This is the part of the field that has always been broken: outcomes data lives in scattered chart notes and never makes it back into the design loop. We've put the data collection where it actually happens, at home, on a phone, by the person who knows the dog best, so your follow-up visits are informed by real data, and the next patient's design is informed by yours.
What this looks like on your calendar
Indicative durations during closed beta. We refine these numbers as we run more cases through the partner CDMO.
Stage 1: Sample to lab
2–3 days
Kit ships to your clinic, samples collected during procedure, courier returns to sequencing partner.
Stage 2: Lab to vaccine
~3 weeks
Sequencing and analysis (7–10 days), your clinician review (under twenty minutes), CDMO manufacturing (~14 days).
Stage 3: Vaccine to outcome
Ongoing
Cold-chain shipment to your clinic, administration on your schedule, owner-driven outcomes tracking on a phone.
FAQ
Who actually administers the vaccine?
Your veterinary oncologist, under your existing clinical judgment and ethics framework. We are a bioinformatics design service. We do not synthesize mRNA, manufacture vaccines, administer treatments, or practice veterinary medicine.
How long does the whole process take?
From kit shipment to a vaccine in your fridge is roughly four weeks end-to-end during closed beta: sample shipping 2–3 days, analysis and design review 7–10 days, CDMO manufacturing about 14 days. These numbers tighten as we run more cases through our partner CDMO.
What does it cost during closed beta?
Pricing during closed beta is handled case-by-case rather than by published rate. Pilot cases are priced at cost rather than at a margin. The goal of this phase is to learn from each case carefully, not to scale revenue.
What tumour types do you accept?
Our pipeline works best for tumours with a reasonable somatic mutation burden. Mast cell tumours, melanoma, osteosarcoma, hemangiosarcoma, and lymphomas have been our primary focus. We'll discuss case fit with you before accepting.
What if I want a second opinion on the design?
The design report is yours regardless of whether you proceed with manufacturing. It includes per-target rankings, source mutations, and confidence calls, enough detail for any bioinformatician you trust to scrutinize the design independently.
What happens if outcome data is concerning?
The clinician dashboard surfaces trends from the owner's daily check-ins before each follow-up visit and flags anything that warrants a clinical look, such as significant drops in appetite, energy, mobility, or photos showing tumor changes, so you can intervene at the next visit, or sooner if needed.
Can a pet owner enroll their dog without their vet's involvement?
No. RosieVaccine works through veterinary oncologists. Owners can join our waitlist to be notified as access expands, but every step, from case acceptance and design review to manufacturing handoff, administration, and follow-up, runs through you.
Ready when you are
Each pilot case is reviewed individually by our scientific and clinical advisors before we agree to proceed. Tell us about your patient and we'll get back to you.
Request a pilot case →Closed beta · Veterinary oncologist–administered
Important
RosieVaccine is an experimental AI-assisted bioinformatics design service operating in closed beta. We do not synthesize mRNA, manufacture vaccines, administer treatments, or practice veterinary medicine in any jurisdiction. Outputs of our pipeline are computational design proposals intended for review and clinical decision-making by a licensed veterinary oncologist. This service does not guarantee any clinical outcome, and individual results will vary substantially. All descriptions on this site represent the current design of our service and planned partner-mediated workflows, not demonstrated clinical capabilities at scale. Always consult your veterinarian before pursuing any cancer treatment for your pet.